Generic Biltricide Praziquantel

Title: Rely on Biltricide Praziquantel to Have Complete Cure from Worm Infections

 

Worm or parasitic infections such as schistosomiasis, blood flukes, and liver flukes can be cured completely by using Biltricide (generic name Praziquantel). As an anthelmintic, it is a proven drug in checking the development and propagation of flatworms in the body. Praziquantel came in the limelight from the scientific labs for parasitological research of Bayer AG in Germany in the mid-1970. It has also been included in the Model List of Essential Medicines of the World Health Organization (WHO).

 

When we consider the pharmacology of Praziquantel, it is found that the drug is absorbed very well from the gastrointestinal tract. The figure is around 80 percent. Praziquantel due to its wide first-pass metabolic process gets into the systemic circulation in comparatively small amounts. In adults, this medication has shown a serum half life of 0.8 to 1.5 hours with normal renal and liver function. However, its metabolites have 4 to 5 hours of serum halflife. It can increase to 3 to 8 hours in those patients who have radically impaired liver function. Urine is the main medium of excretion for Praziquantel and its metabolites (70 to 80%), inside 24 hours after a solitary oral dose. The metabolic process of Praziquantel is accomplished through the cytochrome P450 pathway 3A4. However, there are certain drugs like phenytoin, rifampin, and azole’s antifungals that can stimulate or inhibit Cyp450 3A4 to affect the metamorphosis of Praziquantel.

 

Various studies have confirmed the spectacular effect of Biltricide on patients with schistosomiasis. Patients who were part of these studies experienced reversal of their 90 percent of the damage caused to internal organs due to schistosomiasis within 6 months of taking a dose of Praziquantel.

 

The mechanism of action of Biltricide is not fully known at present. However, the experimental evidence states that the medication increases the permeability of the membranes of parasite cells for calcium ions, thereby stimulating contraction of the parasites that leads to paralysis in the contracted state. The disappearing parasites are then bumped from their place of action in the host organism. They may move into systemic circulation or may be destructed by host immune reaction.

 

You need to take a number of precautions during the Biltricide (Praziquantel) treatment. Regular check-up by a qualified doctor is very essential to monitor the effect of the drug on your condition. Once the treatment gets over, the doctor should check your progress to ensure that the infection is polished off altogether. If your symptoms do not get better even after the full time of treatment or if they deteriorate further, consult your doctor right away.

 

As Biltricide (Praziquantel) causes dizziness or drowsiness, you must be extra careful while driving, operating machines or performing other risky activities. In case of severe dizziness, avoid doing these activities. Reduce your alcohol consumption as it may exaggerate certain side effects of Praziquantel. Follow these simple guidelines to derive utmost benefits from the treatment.